Rat Glial Restricted Precursor Cells

The cerebral cortex plays a key role in memory, learning, consciousness and the understanding of language. Glial Restricted Progenitor Cells, derived from cortical tissue, have the potential to differentiate into Oligodendrocytes or Astrocytes. Isolated from newborn Sprague-Dawley Rats they are cryopreserved at passage 2. Post thaw viability is in the range of 60-70%. Each vial contains approximately 1 million viable cells.

Image 1.  Healthy, Undifferentiated GRP’s - Rat Glial Restricted Progenitors (rGRP’s) isolated from Sprague-Dawley rats, postnatal day 3. The above image shows undifferentiated rat GRP’s characterized by A2B5 (green) staining. Cells nuclei are stained with DAPI (blue).

 

Image 2.  Healthy, mature Astrocytes - Rat Glial Restricted Progenitors (rGRP’s) isolated from Sprague-Dawley rats, postnatal day 3. The above image shows differentiated Astrocytes characterized by GFAP (green) staining. Cells nuclei are stained with DAPI (blue).

 

Image 3.  Healthy, mature Oligodendrocytes - Rat Glial Restricted Progenitors (rGRP’s) isolated from Sprague-Dawley rats, postnatal day 3. The above image shows differentiated oligodendrocytes characterized by GalC (green) staining.  Cells nuclei are stained with DAPI (blue).

Technical Data

Publications

  • Barratt, H. E., Budnick, H. C., Parra, R., Lolley, R. J., Perry, C. N., & Nesic, O. (2016). Tamoxifen promotes differentiation of oligodendrocyte progenitors in vitro. Neuroscience.

Information
Recommended Use Generation of oligodendrocytes and astrocytes
Type Sprague-Dawley rat, postnatal day 3, cortex
Product Unit Cryopreserved vial
Size 1 vial, 1 million viable cells
Storage Liquid nitrogen
Quality Testing Tested for healthy undifferentiated growth, sterility, Mycoplasma, post-thaw viability
Shipping Dry ice

Rat Glial Restricted Precursor Cells - 1M

  • Product Code: GSC-8040
  • Availability: In Stock
  • $485.10


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Tags: rat, GRP, glial, restricted, precursor, cells, primary, neural